The truth in medicine does not exist, since 3500 publications are added every day to the knowledge base of medicine. Each day the truth changes a little. Today, evidence-based medicine with its key methodology of systematic reviews of randomized controlled trials attempts to sift out the valuable ‘true’ information
Month: June 2019
http://dx.doi.org/10.47829/JJGH.2019.1401 The number of patients with inflammatory bowel disease (IBD) is increasing in the worldwide. Thiopurine S-methyltransferase (TPMT) plays a significant role in the metabolism of thiopurine drugs.
Imaging biomarkers are needed to assess modifications in pancreatic adenocarcinoma (PA) induced by stroma-targeted therapies. The study investigates correlations between quantitative diffusion parameters obtained in vivo and ex vivo with a tumour volumetric approach and quantitative pathologic findings including fibrosis, vascular and total nuclear densities in PA
Colonoscopy screening for colorectal adenomatous polyps or cancer has become a worldwide recommendation since this is the third most common human cancer[1-3] resulting in an estimated 49900deaths annually. Furthermore, polyps and cancers have been observed in younger people resulting in recommendations by societies to start screening at age 45 .
Although the international guidelines recommend the CDH1 germline mutations screening in patients at risk of carrying pathogenic mutations, few data exist about the compliance to systematic screening programs carried out in surgical centres
There are quite more than dozens studies in world literature concerning the problems of the quality of life of patients with colorectal cancer in a wide variety of clinical and socio-individual aspects. It is significantly difficult any specific screening and stratified grouping of similar problems in patients with locally advanced cancerboth of the colon and …
To assess the benefits of performing endoluminal forceps biopsy during initial drainage compared to postponed biopsy using two patient management scenarios. Since 2006, 101 consecutive patients with malignant biliary stenosis due to cholangiocellular carcinoma have been followed up. All patients underwent a percutaneous biliary drainage (PBD) procedure and endoluminal forceps biopsy to obtain histological verification …