Month: May 2020

Prevalence of Nocturnal Leg Cramps in Patients with Liver Disease is Higher than with Other Chronic Disease

A nocturnal leg cramps (NLC) is caused by a continuous, involuntary, painful, and localized contraction of a muscle or simply some muscle bundles.NLC is associated with a reduced quality of sleep and a subsequent lower health related quality of life. The purpose of our study is to clarify both prevalence and characteristics of NLC in …

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The Relationship between Pancreatic Fibrosis and Pancrea- tic Cell Apoptosis Induced by Fas/Fas Ligand Pathways in Aly/Aly Mice

In this study, we examined the relationship between the expression of Fas/Fas ligand apoptotic signaling pathway and pancreatic fibrosis in autoimmune chronic pancreatitis of aly/aly mice. The histopathological changes of inflammatory cell infiltration in pancreatitis aly/ aly mice were observed. Immunohistochemistry was used to detect the expression of CD4, CD8, CD45R/B220, F4, Fas/Fas ligand, collagen …

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The Endoscopic Combo Technique: Long-Term Outcomes in Treating Patients with Primary Achalasia

Achalasia is a primary esophageal motility disorder characterized by the absence of esophageal peristalsis and impaired relaxation of the Lower Esophageal Sphincter (LES) in response to swallowing. The annual incidence of achalasia is approximately 1.6 per 100,000 individuals worldwide and prevalence of 10 cases per 100,000 individuals. Patients present usually with progressive dysphagia to solids …

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Quadruple with Omeprazole, Bismuth, Tetracycline and Metroni- dazole Therapy for the Eradication of Helicobacter Pylori: Efficacy in Naive and Previously Treated Patients with Double and Triple Antimicrobial Resistance

To eradicate Helicobacter Pylori (HP) infection itÂ’s necessary to use at least two antibiotics. In patients infected with HP resistant to two or three antibiotics, eradication is more difficult. The objective of this study was to evaluate the efficacy of bismuth quadruple therapy (BQT)-10 days (omeprazole, bismuth, tetracycline-TET, and metronidazole-MTZ) for the eradication for HP …

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Direct Acting Antivirals in Hepatitis C Virus Genotype 3 and Advanced Cirrhosis

Direct-Acting Antivirals (DAAs) have revolutionized the management of hepatitis C infection. However, genotype 3 cirrhosis is still difficult to treat. We report our experience in the management of geno- type 3 cirrhosis with DAA’s. We analysed 111 adult cirrhotics with genotype 3 infection of which 54 (48.6%) had Decom- pensated Cirrhosis (DC). Patients with Compensated

HO-1 as a Dynamic Sensor in the Livers of Chronic Cerebral Hypoperfusion Rats

Heme oxygenases, mainly including heme oxygenase-1(HO-1) and heme oxygenase-1(HO-2), play a key role in protecting from oxidative stress and inflammation associated with vascular disease. Little is known, however, about the roles of HO-1 and HO-2 in the livers of rats with chronic cerebral hypo perfusion. The study aims to evaluate the expression and roles of …

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