Month: February 2022

Clinical Utility of Exosomal Micrornas for Colorectal Cancer

1. Abstract Exosomes are nanometer-sized membrane vesicles secreted by normal or cancer cells, which participate in intercellular communication by transporting RNAs and proteins. Recent studies have found that some differentially expressed microRNAs (miRNAs) in exosomes play key roles in the initiation and development of Colorectal Cancer (CRC) and are potential candidates for CRC detection. In …

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Ceacal Trichuriasis Presenting as Severe Iron Deficiency Anemia: A Case Report and Review of Literature

1. Case Report A 24 years old male with no co morbidities presented to our out-patient department with complaints of exertional shortness of breath and easy fatigability of 6-month duration. On clinical examination he was grossly pale. There was no other significant finding on clinical history and examination. Ha emogram revealed hemoglobin of 6.7 g% …

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Potential of Absorption, Capillary Effect and Sponge-Effect in Endoscopic-Assisted Therapy for Leaks and Fistulas

1. Abstract 1.1. Introduction: Anastomotic leaks and fistulas as well as perforations do lead to increased morbidity and mortality. Several interventional endoscopic techniques such as stents, clips, endoscopic suturing and endoscopic vacuum therapy, can help in reducing an unfavorable outcome of these patients, using a differentiated management of leakages. An important feature of these therapeutic …

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The Association Between ABO Blood Group Distribution and Helicobacter Pylori Infection: A Cross-Sectional Study

1. Abstract 1.1. Purpose: H. pylori infection has always been associated with the external factors of hygiene, but there is a lack of credible information about its association with ABO blood group. We attempted to establish the role and involvement of internal factors including age, blood group and electrolytes in manifestation of this disease.

Synchronous Pancreatic Neuroendocrine Tumor and Pancreatic Cyst: A Case Report

1. Abstract Synchronous pancreatic neuroendocrine tumor (pNET) and pancreatic cyst are very rare. Herein, we report a case of pNET combined with a pancreatic cyst in a 49-year-old female. The patient first presented with a complaint of persistent pain in the right upper abdomen. As a follow-up, CT scan was performed that showed a solid …

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Assets of Circulating Extracellular Vesicles for Early Diagnosis and Prognosis of Gastric Cancer by Liquid Biopsy

1. Abstract Gastric cancer (GC) is an important human cancer, which needs new biomarkers for early diagnosis in order to improve the patients outcome. The aim of this review is to stress the huge interest of extracellular vesicles circulating into blood and other body fluids, as potential candidates for early diagnosis of gastric cancer. After …

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Primary Fistulotomy and Surgical Drainage Abscess is Associated with Low Fistula Recurrence Rate

1. Abstract 1.1. Background: Anorectal abscesses have become a common surgical problem, approximately one third of them also have anal fistulae; management can be conservative with antibiotics or needle aspiration and simple drainage with local anesthesia, considering them sufficient to remit the acute condition of this pathology. However, this line of treatment has been associated …

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Prolonged High Dose Esomeprazole for the Treatment of Chronic Cough in an Israeli Adult Population – An Open Label Study

1. Abstract 1.1. Background: Chronic cough is considered to be part of the Gastroesophageal Reflux Disease (GERD) spectrum. However, the response rate to standard dose Proton Pump Inhibitors (PPI’s) is poor. Our aim was to evaluate the response rate of chronic cough to an extended course of high dose PPI’s and to identify predictors of …

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