Month: October 2022

A Unusual Case of Acute Abdomena

1. Introduction The pathological and embryological origin of Meckel’s diverticulum was first described in 1809 [1]. The omphalomesenteric duct connects the yolk sac to the midgut of the developing fetus. Meckel’s diverticulum occurs when there is a failure of obliteration of this primitive vitelline loop.

Single Center Analysis of Epidemiology and Outcome of Pancreatitis

1. Introduction Acute pancreatitis (AP) is one of the most common indications for hospitalization and may potentially lead to fatal outcomes [1]. The clinical presentation often lies on a spectrum of severity from mild abdominal pain to severe shock and multiorgan failure. This variation in presentation often creates obstacles in diagnosis by clinicians and may …

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BCHE As A Prognostic Biomarker For Stomach Adenocarcinoma And Correlates With Immune Cells Infiltration

1. Abstract 1.1. Background: Bcylcholinesterase (BCHE) is a nonspecific esterase synthesized by the liver that promotes cell proliferation and differentiation. Several studies suggested that BCHE is related to the occurrence and development of some tumors. However, the expression of BCHE in stomach adenocarcinoma (STAD) and its regulatory mechanism remains elusive.

Signet Ring Cell Colorectal Cancers Portend an Aggressive Biology: A 17-Year Analysis of Operable Colorectal Cancers at a Tertiary Hospital in Pakistan

1. Abstract 1.1. Introduction: Primary signet ring cell carcinoma (SRCC) is a rare variant of colorectal cancer, reportedly comprising 0.1%- 2.6% of all colorectal cancers. Due to presentation with symptoms occurring later in the course of the disease, the overall survival is reportedly poorer than that of colorectal adenocarcinoma. Anecdotal evidence suggests that Southeast Asian …

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The Diagnostic Challenge of Recurrent Oral Aphtosis in Children: One Symptom, Many Diagnoses

1. Abstract Recurrent oral ulcers (OU) are a common manifestation in infancy affecting up 40% of children. The first step necessary for the diagnosis is the search for associated systemic symptoms. Recurrent aphthous stomatitis (RAS) is the most common diagnosis in patients with isolated OU, being a diagnosis of exclusion. Among patients with associated symptoms, …

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The Protect Effects of Sodium Ferulate against Inflammatory Bowel Disease (IBD) Through Repress JAK2/STAT3 Signaling In Young and Aged Mice

1. Abstract Inflammatory bowel disease (IBD) is a type of immune-mediated intestinal inflammation caused by a variety of environmental, genetic and epigenetic risk factors. Up to now, there has been no effective drug treatment for IBD in elderly patients. Cytokines (such as IL-6) have been reported to activate Janus tyrosine kinase2 (JAK2)/signal transducer and activator …

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Primary Umblical Endometriosis Masquerading as a Painful Umblical Nodule: A Case Report

1. Abstract 1.1. Background Endometriosis is the presence of endometrial tissue outside the uterine cavity. Although the pelvis is the most common site of occurrence, extra pelvic areas like the umbilicus are also reported. Primary Umbilical Endometriosis is very rare; the reported incidence is 0.5-1% of all extra pelvic diseases. It is often a second …

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