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Intrahepatic Cholestasis and Fetal Demise: Association or Causation?

Data are conflicting regarding a cause and effect relationship between ICP and stillbirth. On one hand, the data show a higher risk of stillbirth at term without an effective test that might predict demise except high level of bile acids. On the other, even if the stillbirth rate is reduced by a late preterm birth, …

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Prognosis and Treatment Strategy of Early Gastric Cancer with Signet Ring Cell Histology

The prognosis of early gastric cancer (GC) with signet ring cell (SRC) histology comparing with other subtypes remains a matter of debate. Kim et al. indicated that early GC with SRC differs clinical course and prognosis from non-SRC.1 They found that mucosal and submucosal GC with poor differentiation had 6.3% and 30% of lymph node …

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Volumetric-Based Analysis of In-Vivo and Ex-Vivo Quantita-tive MR Diffusion Parameters in Pancreatic Adenocarcinoma: Correlation with Pathologic Findings

Imaging biomarkers are needed to assess modifications in pancreatic adenocarcinoma (PA) induced by stroma-targeted therapies. The study investigates correlations between quantitative diffusion parameters obtained in vivo and ex vivo with a tumour volumetric approach and quantitative pathologic findings including fibrosis, vascular and total nuclear densities in PA