Volume 5

Resection of Fourth Segment of Liver as a Cause of Hepatoblastoma in A 8 Month- Old-Boy

Clinical Image

1. Abstract
Intraductal papillary neoplasia of the bile ducts (IPN-B) is a rare intracanal tumor characterized by papillary proliferation of the biliary
epithelium responsible for more or less abundant production of mucus, causing dilation of the duct [1]. IPN-B is the “biliary” equivalent
of TIPMP. MRI cholangiography and transcutaneous abdominal ultrasound are the best examinations to suggest the diagnosis in the

Unexpected Esophageal Mucosal Defects After Peroral Endoscopic Myotomy (POEM)

Case Report

1. Abstract
Intraductal papillary neoplasia of the bile ducts (IPN-B) is a rare intracanal tumor characterized by papillary proliferation of the biliary
epithelium responsible for more or less abundant production of mucus, causing dilation of the duct [1]. IPN-B is the “biliary” equivalent
of TIPMP. MRI cholangiography and transcutaneous abdominal ultrasound are the best examinations to suggest the diagnosis in the

Intraductal Papillary Neoplasia of the Bile Ducts (IPN-B): About a Case

Case Report

1. Abstract
Intraductal papillary neoplasia of the bile ducts (IPN-B) is a rare intracanal tumor characterized by papillary proliferation of the biliary
epithelium responsible for more or less abundant production of mucus, causing dilation of the duct [1]. IPN-B is the “biliary” equivalent
of TIPMP. MRI cholangiography and transcutaneous abdominal ultrasound are the best examinations to suggest the diagnosis in the

Changes in Metabolic Processes in The Gastric Mucosa in The Pathogenesis of the Formation of Acute Ulcers in Acute Small Intestinal Obstruction

Research Article

1. Abstract
1.1. Introduction: Acute small bowel obstruction is a problem of modern surgery. It is not possible to study morphological and functional
changes in the walls of the stomach in acute small bowel obstruction on clinical material, performing a biopsy in the dynamics of the development of the disease. Therefore, our work is experimental.

Quantum Nature of Coronavirus and Method of Treatment

Review Article

1. Abstract
Work on the coronavirus is trying to produce vaccines of various types. Those are vaccines containing inactivated or killed viruses, vaccines with viral fragments, which are intended to sensitize the immune system to specific virus subunits. Vaccines based on RNA or DNA nucleic acids, which contain a synthesized stretch of viral mRNA.

Infective Suppurative Thrombosis in the Left Portal Vein After Acute Appendicitis

Clinical Image

1. Clinical Case
Postoperative complications can occur. Most of them are frequent and we are used to dealing with them, but there are others that seem to appear only in a few posts, and when they happen to your patient you cannot explain why.

Helicobacter Pylori Detection Among Sudanese Patients Diagnosed with Conlon Polyps and Colon Cancer Using Immunohistochemistry Technique

Research Article

1. Abstract
1.1. Aim: The aim of this study is to make our contribution to the study of acute generalized peritonitis of typhus origin at the Kankan Regional Hospital. Typhoid perforation is defined as the opening of a hollow viscus in the abdominal cavity due to salmonella.
1.2. Methodology: We carried out a 6-month prospective study from June 1, 2019 to November 30, 2019 inclusive.

Acute Peritonitis Generalized by Typhoid Perforation at Kankan Regional Hospital

Review Article

1. Abstract
1.1. Aim: The aim of this study is to make our contribution to the study of acute generalized peritonitis of typhus origin at the Kankan Regional Hospital. Typhoid perforation is defined as the opening of a hollow viscus in the abdominal cavity due to salmonella.
1.2. Methodology: We carried out a 6-month prospective study from June 1, 2019 to November 30, 2019 inclusive.

MEFV Gene Mutations and Pathologic Gene Polymorphism in Cases with Inflammatory Bowel Diseases

Editorial

1. Editorial
1.1. The Genetic Characteristics of Inflammatory Bowel Diseases and Familial Mediterranean Fever Inflammatory bowel diseases (IBD) are chronic, repetitive diseases caused by regulation defects of the mucosal immune response, which increases against the bacterial antigens in the bowel lumen of patients with genetic susceptibility [1].

Hepatitis B Virus X Protein and Hepatitis C Virus Core Protein Cooperate to Inhibit P16 Expression Via DNA Methylation

Research Article

1. Abstract
Coinfection with hepatitis B virus (HBV) and hepatitis C virus (HCV) is often associated with a higher risk of hepatocellular carcinoma (HCC). Here, we found that HBV X protein (HBx) and HCV core protein cooperate to inhibit p16 expression via DNA methylation in human hepatoma cells. For this purpose, they additively upregulated both protein levels and enzyme activities of DNA methyltransferases (DNMTs) 1, 3a and 3b and induced promoter hypermethylation of p16. As a result, HBx and HCV core protein in combination activated the Rb-E2F pathway to stimulate cell cycle progression from G1 to S phase, resulting in an increase in cell proliferation.