Epidemiological Profile and Clinical Spectrum of Hepatitis B-Ten Years Experience at Tertiary Care Centre of Northeren India
1.1. Introduction: Hepatitis B virus (HBV) infection, a pan global health problem, has already effected one-third of the world popula- tion. India harbours around 40 million HBV carriers, thus account- ing for 10–15% share of total pool of HBV carriers of the world. Every year over 100,000 Indians die due to illnesses related to HBV infection
1.2. Aims and Objectives: To study the Epidemiological profile and Clinical spectrum of patients with Hepatitis B virus infection.
1.1. Introduction: Viral hepatitis is an important health problem in India and is caused by Hepatitis A, B, C, D, E and G virus which can lead to acute or chronic infection.
1.2. Aims & Objectives: To determine the genotype of chron- ic hepatitis C patients attending Department of Gastroenterology, PGIMS Rohtak.
1.3. Summary and Conclusions: Our study highlights that Gen- otype 2 is rare in India and Genotype 3 is most common genotype which is difficult to treat Genotype with oral antiviral therapy.
Alcohol Induced Gut Microbiota Modulation: The Role of Probiotics, Pufas, and Vitamin E in Management of Alcoholic Liver Disease
Chronic alcoholism is a global healthcare problem resulting in 3.3 million deaths or 6% of all deaths. In India, the alcohol consumption rates range from 23-73% in males and 24-48% in females. The liver suffers the greatest degree of injury, because it is the primary site of its metabolism, along with gut and brain. Alcohol metabolism in intestines may result in disruption of tissue homeostasis causing a chronic state of intestinal inflammation.
Temporary Spontaneous Disappearance of Diffuse Large B Cell Lymphoma in Patient with Hepatitis C Virus
An 80-year-old male, diagnosed with chronic hepatitis C and received interferon (IFN) treatment, but was a non-responder. Abdominal contrast CT for screening revealed a hypovascular liver tumor in the liver with para-aortic and intraperitoneal lymphadenopathy. Pathologically, biopsy of the tumor revealed mild infiltration of only inflammatory cells in the portal region and no tumorous change was recognized.
Low Density Lipoprotein Cholesterol May Be a Key Independent Risk Factor for Asymptomatic Gallbladder Stone Disease in Non-Alcoholic Fatty Liver Disease Patients in Northwest China: A Case-Control Study
1.1. Background: Previous studies reported that Non-Alcoholic Fatty Liver Disease (NAFLD) is associated with gallbladder stone disease (GSD). The study aimed to detect the key factors influencing the formation of new-onset GSD among the NAFLD patients.
1. Case Report
Mortality rates of COVID-19 continue to rise across the world. The majority of patients dies from Adult Respiratory Distress Syndrome (ARDS), pulmonary embolism and from cytokine storm syndrome. We describe the case of 52 years old women, with ARDS and Cytokines Storm Syndrome (CSS) who survived.
1. Short Communication
Acute respiratory distress can occur in patients with COVID-19 disease due to viral replication of SARS-COV-2 and an uncontrolled immune inflammatory reaction. We compared the efficacy of intravenous methylprednisolone and intravenous dexamethasone on mortality rate in severe COVID-19 patients with pneumonia and hypoxemia using the new 4C mortality score on admission and on discharge .
Hepatic Cysts with Cholesterol Crystal Formation: An Unusual Mimicker of Cyst Infection in A Patient with Autosomal Dominant Polycystic Kidney Disease
Hyperechoic echogenicity in a hepatic cyst is a sign of cyst infection. We report a case of autosomal dominant polycystic kidney disease with polycystic liver disease where the hepatic cyst showed glittering spots. Cyst fluid analysis revealed them as cholesterol crystals.
1.1. Objective: Spontaneous Bacterial Peritonitis (SBP) is a big complication of severe complication “ascites” in patients with cirrhosis. There are three clinical forms of SBP (1982) – latent, classical and fulminant. Classic symptoms of peritonitis in SBP are usually absent. Diagnosis of SBP is established if polymorphonuclears (PMNs) in ascitic fluid are >250/mm3 – SBP (PMNs >250/mm3 and positive bacterial cultures) and culture negative neutrophylic ascites (CNNA) or bacterascites (positive bacterial cultures from ascitic fluid and PMNs <250/mm3).
Change of the Ascitic Fluid Total Protein in Natural Progression of Liver Cirrhosis and Serum Ascites Albumin Gradient in Patients with Spontaneous Bacterial Peritonitis Versus Patients with Cirrhosis and Sterile Ascites
1.1. Background: Spontaneous Bacterial Peritonitis (SBP) is a big complication of liver cirrhosis with ascites. Ascitic Fluid Total Protein (AFTP) is still used to determine the risk of SBP in cirrhotic patients with ascites. There are single reports of the role of serum-ascites
albumin gradient (SAAG) in the diagnosis of SBP.
1.2. Aim: The aim of the study is to determine whether AFTP decline in natural progression of liver cirrhosis (predisposition of SBP) and to determine whether SAAG is significant higher in patients with SBP than in patients with liver cirrhosis and sterile ascites.