Volume 6

Impact of Hyponatremia On the Severity of Cirrhosis at The Brazzaville University Hospital Center

Research Article

1. Introduction

Cirrhosis is a fibrosing disease that constitutes the terminal stage of chronic liver pathologies. It is a major public health problem. Indeed, the incidence in the world varies from 1.3 to 5.9. In France, the annual incidence is 150 to 200 cases per million inhabitants [1].

Safety Profile of Tenofovir in Hepatitis B Pregnant Patients

Research Article

1. Abstract

1.1. Introduction: Hepatitis B Virus (HBV) is a major cause of chronic hepatitis, cirrhosis and hepatocellular carcinoma. There are three possible routes of transmission of HBV from infected mothers to infants: transplacental transmission of HBV in uteri, natal transmission during delivery or postnatal transmission during care of infant or through breast milk.

Robotic-Assisted Gastric GIST Resection: A Single Center Experience

Research Article

1. Abstract

1.1. Aims: Gastrointestinal Stromal Tumors (GISTs) are the most common mesenchymal tumors, representing 1-3% of all gastrointestinal cancer. Surgical resection is the only curative treatment. Minimally invasive approaches such as laparoscopic and robotic-assisted resections for gastric GISTs have proved to be oncologically and surgically safe. We report here a case series of robot-assisted gastric GISTs resections in our center.

Nomogram Predicts the Cancer-Specific Survival of Patients with Gastrointestinal Mixed Adenoneuroendocrine Carcinoma

Research Article

1. Abstract

1.1. Background: Our study aims to establish a nomogram model to predict Cancer-specific survival of patients with gastrointestinal mixed adenoneuroendocrine carcinoma.

Results of Frey’s Procedure for Chronic Pancreatitis: A Retrospective Single-Center Study in Vietnam

Research Article

1. Abstract

1.1. Introduction: Surgical treatment of chronic pancreatitis is indicated for intractable pain. Frey’s method is an accepted treatment for this disease. The present study aimed to describe a single-center experience in the treatment of Frey’s procedure for chronic pancreatitis.

Imaging Findings and Differential Diagnosis of Hepatic Sinusoidal Occlusion Syndrome and Budd-Chiari Syndrome

Research Article

1. Abstract

1.1. Objective: To retrospectively analyze the clinical and imaging manifestations differential points between hepatic sinusoidal obstruction syndrome (SOS) and Budd-Chiari syndrome (BCS).

1.2. Material: The clinical symptoms, laboratory examination and imaging findings of 15 cases of hepatic sinusoidal obstruction syndrome and 33 cases of Budd-Chiari syndrome were statistically analyzed, find the identification points. The study used the Fisher test, P values of 0.05 or less were considered to indicate significant differences. The retrospective study was approved by the hospital’s ethics committee.

Effects of Different Capsule Types for Oral Application of Active Substances – Investigations with Organ-Specific Cells

Research Article

1. Abstract

1.1. Background: A capsule is a solid dosage form that delivers a defined dose of an active ingredient. Most capsules are made for oral application by mouth with subsequent swallowing. Capsule materials for the shell are not only of importance for the release of active ingredients, but should also be without any impact on the digestive tract and the active ingredient itself. Some capsule materials have been shown to possess unwanted effects after digestion.

Liver Injury as Mortality Risk Factor in Sars-Cov-2

Research Article

1. Abstract

1.1. Background: The current COVID-19 pandemic has put all health units in crisis. The easy transmissibility facilitated the fast spread to all countries, and Guatemala was not the exception. By May 2020 almost 229 thousand cases were reported, with 3.2% of case fatality. Among the principal mortality risks factors there are: advance age, diabetes mellitus, cardiovascular disease, etc.

The Role of Prebiotics on Inflammatory Bowel Disease: A Systematic Review

1. Abstract

1.1. Background: Inflammatory Bowel Diseases (IBD) are a set of disorders of idiopathic and multifactorial etiology, composed of two main entities: Ulcerative Colitis (UC) and Crohn’s Disease (CD). The pathophysiology relies on inflammatory responses of the intestinal Wall.

Review of Cancer – Related Cachexia: Definition, Physiopathology and Treatment

1. Abstract

The deterioration in nutrition status is frequently seen in cancer patients. Cancer- related Cachexia (CC) is a common multifactorial condition that highly impacts on survival and quality of life of cancer patients. CC has been categorized into three phases: pre-cachexia, cachexia and refractory cachexia.