Volume 7

Dress Syndrome in a Patient on Sulfasalazine for Hemorrhagic Rectocolitis: A Case Report

Case Report

1. Abstract

Sulfasalazine is an immunomodulatory drug used in the treatment of various dysimmune diseases including the intestinal bowel disease. Sulfasalazine is known to cause sulfasalazine-induced hypersensitivity syndrome (SIHS), also known as drug reaction with eosinophilia and systemic symptoms (DRESS).

Self-Expandable Metal Stents for the Management of Gastric Outlet Obstruction: Experience from A Tertiary-Care Facility in Pakistan

Research Article

1. Abstract

1.1. Aim

Gastric outlet obstruction is commonly considered as advanced malignancies of the stomach, duodenum, pancreas, hepatobiliary, and ampullary regions. Surgical bypass and chemotherapy are the common treatment modalities for gastric obstruction. This study was done to determine the outcomes of self-expandable metal stents in patients with gastric outlet obstruction.

Intestinal Ischemia Following Cardiac Surgery: An Unusual Clinical Presentation

Research Article

1. Abstract

Mesenteric ischemia is a dreadful complication with a high mortality rate. Early diagnosis and management is mandatory to improve prognosis.

We report a 72-year-old woman who has undergone a bioprosthetic aortic valve replacement. She presented an abdominal pain associated to an occlusive syndrome. Angio-CT scan has found initially a functional bowel obstruction without mesenteric ischemia. 3 days later, she became febrile and her abdominal distension increase. The fellow up Angio-CT scan revealed a pneumoperitoneum suggestive of a bowel perforation. A diagnostic laparotomy had found two ischemic ileal perforations. The ischemic origin was confirmed by histo-pathological examination. She underwent segmental ileal resection with end-to-end anastomosis. The follow up was favourable.

Endoscopic Radiofrequency Ablation of Fiatula in Ano (VAAFT-Fistura) In The Era of Surgical Innovation. A Serial Prospective Evaluation of 10 Patients

Review Article

1. Abstract

1.1. Background: Fistula in-ano is an abnormal chronic infected tunnel ( tract ) between the rectum or the anal canal and perianal skin usually ,with granulation tissue which connecting a primary orifice ( internal ) to a secondary one ( external) .This morbid antity represents a dilemma for both ,patients and surgeon-proctologists because of postoperative issues occurrence such as fecal incontinence .The surgical management of this infectious condition has emerged nowadays ,by emphasing new surgical techniques that preserve anal sphincter’s integrity and functional Over the last decade, numerous techniques sparing anal sphinters have gained popularity such as endoscopic approach ( VAAFT ), Laser, fibrin glue, transanal advancement flap repair [1, 6]. In the same perspective, we are presenting in this paper, our preliminary outcomes of a combination of endoscopic approach (VAAFT) with Radifrequency Ablation of the fistula’s tract that we nicknamed with the acronym of VAAFT-FisTura).

Endoscopic Pilonidal Sinus Treatment Combined To Radiofrequency Ablation (Epsit-Fistura), A Perspective of Surgical Innovation

Review Article

1. Backround and Aim

Pilonidal Sinus also known as pilonidal cyst dease, sacrococcygeal fistula, intergluteal pilonidal disease is, a common disease of the sacrococcygeal region affecting mosly obese and sedentary young individuals of both genders.

Enhancing A Radiomics-Based Pathological Response Prediction for Locally Advanced Rectum Cancer

Short Communication

1. Abstract

1.1. Aims: This study aims to further enhance a validated radiomics-based model for predicting pathologic complete response (pCR) after chemo‑radiotherapy (CRT) in LARCs for use in the clinical practice.

1.2. Methods: A generalized linear model (GLM) to predict pCR in LARC patients previously trained in Europe and validated with external inter-continental cohort (59 patients) was first examined with further 88 intercontinental patient datasets to assess its reproducibility; new radiomics and clinical features, and validation methods were investigated. The patients were divided into training group (75%) and validation group (25%) according to their demographic.

Pros and Cons of Iron Deficiency and Iron Deficiency Anaemia

Short Communication

1. Short Communication

Iron deficiency anaemia (IDA) and iron deficiency (AD) are very common specially in low-income countries [1]. People can suffer from symptoms of anaemia in the absence of anaemia itself if they have decreased iron stores as red blood cells and tissue will not receive enough iron from the plasma when iron stores are low.

Atypical Initial Presentation of Crohn’s Disease: Inflammatory Ampullary Pseudotumor Causing Obstruction of the Common Bile Duct – A Case Report and Review of the Literature of Pseudotumors Linked to Crohn’s Disease

Case Report

1. Introduction

Crohn’s disease extraintestinal manifestations have been well described in the literature and in many cases may precede the diagnosis of the disease. However, the findings of an inflammatory pseudotumor, at different organs of the body, is rare especially those presenting in the peripancreatic (such as ampulla of Vater) and pancreatic area, and obstructing the biliary tract. We report a rare case of Crohn’s disease manifesting by a peripancreatic pseudotumor, at the level of the ampulla of Vater, causing an initial clinical presentation of an obstructive jaundice, in an elderly man, in whom a Whipple procedure was performed due to the high suspicion of a malignant peripancreatic tumor.

Malignant Tracheo-Esophageal Fistula: Case Report

Case Report

1. Abstract

A 64-year-old male patient diagnosed with locally advanced esophageal cancer complicated by tracheo-esophageal fistula. Esophagogastroduodenoscopy (EGD), contrasted CT and PET-CT showed mid esophageal lesion. Bronchial fibroscopy (BFS) revealed protruding nodular mass invasion from esophagus at the distal trachea and fistula.

Salvia Miltiorrhiza Ameliorates Disease Progression in Dextran-Sodium-Sulfate Induced Colitis in Mice

Research Article

1. Abstract

Salvia miltiorrhiza (SM, or Danshen) extract has been approved by China FDA for the treatment of cardiovascular and cerebrovascular diseases owing to its potent anti-inflammatory effects. Whether SM may be used to treat Inflammatory Bowel Disease (IBD) remains elusive. In the current study, Dextran-Sodium-Sulfate (DSS) induced colitis in mice was used as a model of IBD, and SM was given orally for 7 days.